Immunohistochemical Revealing of Alpha-Synuclein in Synaptic Contact Area of Hippocampal CA<sub>3</sub> Zone
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چکیده
منابع مشابه
The effect of ketamine on synaptic transmission and synaptic plasticity in CA1 area of rat hippocampal slices
The effect of ketamine (1-100 µM), which has NMDA receptor antagonist properties, on synaptic transmission and long-term potentiation (LTP) in CAl area of rat hippocampus was examined in vitro. Field potentials were recorded in pyramidal cell layer following Schaffer collateral stimulation. Primed-burst stimulation (PEs) was used for induction of LTP. The amplitude of population spiks (PS) was ...
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Parkinson's disease is a neurodegenerative disorder characterized by the death of dopaminergic neurons and by accumulation of alpha-synuclein (aS) aggregates in the surviving neurons. The dopamine catabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) is a highly reactive and toxic molecule that leads to aS oligomerization by covalent modifications to lysine residues. Here we show that DOPAL-induce...
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ژورنال
عنوان ژورنال: Journal of Anatomy and Histopathology
سال: 2018
ISSN: 2225-7357
DOI: 10.18499/2225-7357-2018-7-2-23-28